Migraines and chronic irritable bowel syndrome: studies show genetic similarities

Migraines and chronic irritable bowel syndrome: studies show genetic similarities

Migraines, headaches and irritable bowel syndrome could be related to our genetics
If people suffer from headaches or migraines all the time, their quality of life will be badly affected. Anyone who has had a severe headache knows how uncomfortable such a condition is. It is often not possible to do even the smallest of everyday tasks. Researchers have long been looking for the reasons that trigger migraines and severe headaches. Now the doctors found a gene that could be related to the diseases.

Unbearable headaches and migraines can make life hell. With such diseases, it is not possible to follow a normal daily routine. Researchers are now trying to find out what the causes of such diseases are in an investigation. The doctors at "Istanbul University" found that there could be a connection between headache and irritable bowel syndrome. We discovered a gene giving that favors both diseases, the research team said in a press release published by the American Academy of Neurology.

Genetics favor headache, irritable bowel syndrome and tension headache
Since headache and irritable bowel syndrome share similar conditions and the causes of both diseases are unknown, the possible connection discovered is quite encouraging. Our genetics could favor these diseases, explains study author Dr. Derya Uluduz from "Istanbul University". The current results open up new treatment options that could help with both disorders. The new study included 107 people with migraines, 53 subjects with tension headache, 107 test subjects with irritable bowel syndrome and 53 people without any of the impairments, the doctors explain. People with migraines had irritable bowel syndrome about twice as often (54 percent) compared to subjects with tension headaches (28 percent). Of the people with irritable bowel syndrome, 38 subjects also had migraines and 24 people also had tension headaches, the experts explain.

Affected people differ from healthy people by at least one gene
According to their own research, the researchers focused on genetics, in particular the serotonin transporter gene and the serotonin receptor 2A gene. The authors of the study found that people with irritable bowel syndrome, migraines or tension headaches had at least one gene that is different from the genes of people who do not have any of these disorders. Further studies are needed to explore this possible connection, says Dr. Uluduz. The discovery of common genes could open new future treatment strategies for these chronic diseases.

Irritable bowel syndrome is the most common chronic gastrointestinal disease worldwide
Irritable bowel syndrome causes symptoms such as abdominal pain, cramps, bloating, flatulence, diarrhea or constipation and is the world's most common chronic gastrointestinal disorder, according to the researchers. In America alone, about 45 million people are affected by the disease. The exact cause of the chronic disease is not yet known and the disease has not even been diagnosed in many people, explains the expert. (as)

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